These essays examine how some perennial problems in philosophy and religion are significant for understanding contemporary life. Issues discussed include: capitalism; public philosophy; man-made mass death; psychoanalysis; feminism; fundamentalism; and the desire to be happy.

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

Book reviewed in this article: Ethical Issues in Social Research. Edited by Tom L. Beauchamp, Ruth R. Faden, R. Jay Wallace, Jr., and LeRoy Walters. Baltimore: The Johns Hopkins University Press, 1982. xii + 436 pp. $25.00 (hardcover); $8.95 (paper). Ethics of Human Subject Research. Edited by Allan J. Kimmel, Jr. San Francisco: Jossey‐Bass, 1981. 106 pp. $6.95 (paper). Social Research Ethics. Edited by Martin Bulmer. New York: Holmes & Meier, 1982. xiv + 284 pp. $39.50 (hardcover); $14.50 (paper). (...) The Ethics of Social Research: Field‐work, Regulation and Publication. Edited by Joan E. Sieber. New York: Springer‐Verlag, 1982. x + 187 pp. $23.50 (hardcover). The Ethics of Social Research: Surveys and Experiments. Edited by Joan E. Sieber. New York: Springer‐Verlag, 1982. xii + 249 pp. $23.50 (hardcover). (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Kennedy Institute of Ethics Journal 10.2 (2000) 171-174 [Access article in PDF] Bioethics Inside the Beltway The Oversight of Human Gene Transfer Research LeRoy Walters Jesse Gelsinger's death last September in a gene transfer study being conducted at the University of Pennsylvania has helped to spark a national debate. In part, this debate parallels the broader discussion of how human subjects research should be reviewed and regulated in (...) the United States. However, human gene transfer research is one of a handful of biomedical technologies that seem to deserve special attention, at least in the early years of their development.The major participants in the national debate on human gene transfer include the National Institutes of Health (NIH), the Food and Drug Administration (FDA), the National Bioethics Advisory Commission, members of Congress, biotechnology and pharmaceutical companies, disease-oriented advocacy groups, reporters, and academics. At the December 1999 meeting of the NIH Recombinant DNA Advisory Committee (RAC), the protocol that involved Jesse Gelsinger was a central focus of discussion, but other topics emerged as well. One ad hoc panel reviewed adverse events that had occurred in other research protocols using adenovirus vectors, while a second proposed changes in the general system for reporting adverse events to NIH and the RAC.During the first several months of the year 2000, the United States Congress also became involved in the human gene transfer debate. In February, Senator Bill Frist (R-TN) convened a hearing to which Jesse Gelsinger's father, representatives of NIH and FDA, and several other witnesses were invited. At approximately the same time, the House Commerce Committee and its Subcommittee on Oversight and Investigations initiated their own inquiries, asking the Office of Inspector General at the Department of Health and Human Services to review the oversight roles of NIH and FDA. In March and April, the House committee also wrote directly to the NIH Director, the FDA Commissioner, and the President of the University of Pennsylvania, requesting extensive documentation on gene transfer, in general, and the trial in which Jesse Gelsinger was involved, in particular. Congressman Henry Waxman (D-CA) and Senator Edward Kennedy (D-MA) have also raised questions and proposed solutions in multiple letters to the NIH Director and the Secretary of Health and Human Services. [End Page 171]The major general questions that have emerged from this discussion are the following:(1) What kinds of information about adverse events should be reported by researchers or sponsors during the course of human gene transfer trials?(2) To what group or groups should adverse-event information be reported? How often and in what ways should the information be analyzed?(3) Should the information about adverse events remain confidential, or should it be discussed publicly?(4) How can the disclosure and consent process in gene transfer trials be improved?(5) Which federal agency should have primary responsibility for overseeing human gene transfer research, and how can it best fulfill its oversight role?How these questions are answered will have immediate relevance to the field of human gene transfer research as it enters into its next phase. At the same time, the models that are created for this important cutting-edge field also may be useful in other complex or controversial arenas of biomedical research, for example, xenotransplantation or human embryonic stem-cell research. In addition, the lessons learned from this one important area of human subjects research may suggest ways to improve protections for all the volunteers who make clinical research--and medical progress--possible.In the remainder of this article, I will turn from reporting, in as objective a way as possible, on the status of the public policy debate about human gene transfer research to suggesting measures for improving the current oversight system for such research. My initial general recommendation is that we should not expect a single regulatory agency to be solely responsible for a field as large and dynamic as human gene transfer research. Rather, there should be some helpful redundancy or, to change the metaphor, checks and balances in the public oversight of this field. Thus, an... (shrink)

The individualism and restless mobility of modernity have become disorienting and frightening. Our nostalgia for premodern times when natural bonds to kith and kin were unshakable continues to surface, most recently in the popular phenomenon of support groups. On Community examines this crucial philosophical issue of community for the postmodern mind by presenting 13 readable, original essays by some of the top experts currently working on this problem. The first four essays, by Eliot Deutsch, R. W. Hepburn, Hilary Putnam, and (...) Leroy S. Rouner, examine philosophies of community, emphasizing metaphysical analysis and definition of the nature of community. The second section considers the theme in a cross-cultural context. Merry I. White, Katherine Platt, Benjamin Schwartz, and Huston Smith illustrate in this section the various ways in which community is understood and experienced in Japan, North Africa, China, and India. The final section, which contains contributions by Patrick Hill, Jurgen Moltmann, Catherine Keller, and George Rupp, explores the future of community, focusing on community building in Western societies. While the authors represent diverse interests, they also share common ground. Virtually all agree that a creative community needs some form of individualism in order to make a community effective. And there is a consensus among the essays that community is a good thing and that the quest for community in our time is a significant fact. Finally, the contributors suggest that the critique of the liberal view of the autonomous individual, in vogue in recent years, now seems to have waned. (shrink)

Le rôle de David Hume dans la philosophie moderne, par A. L. Leroy.--The enlightenment of David Hume, by E. C. Mossner.--Hume and Jurieu: possible Calvinist origins of Hume's theory of belief, by R. H. Popkin.--Hume: philosopher or psychologist? A problem of exegesis, by T. E. Jessop.--L'astrazione nella filosofia di Hume, di M. Dal Pra.--Infinite divisibility in Hume's "Treatise," by A. Flew.--Note a "La rgola del gusto," di E. Migliorini.--Kant, Hamann-Jacobi and Schelling on Hume, by P. Merlan.--Bibliografia humiana dal 1937 (...) al 1966, di E. Ronchetti. (shrink)

La derni re dition des Lettres sur les animaux, ouvrage de l'encyclop diste mineur Charles-George Le Roy, date de 1896. Cette nouvelle dition propose une pr sentation tr s respecteuse de la pens e originale de l'auteur, elle pr cise dans quelles circonstances les divers l ments du livre furent successivement publi s et retrace son volution depuis les articles HOMME (Morale) et INSTINCT de l'Encyclop die jusqu' l' dition compl te de 1802. L'introduction situe les Lettresdans l'uvre de Le (...) Roy qui, comptant l' criture parmi ses activit s, fut d'autant plus m l aux conflits d'id es de l' poque. Des documents in dits permettent d' tablir avec exactitude combien Le Roy a su mettre profit ses fonctions de lieutenant des chasses des Parcs de Versailles pour exercer ses talents d'auteur. A la lumi re de divers autres documents, et parmi eux des in dits, il appara t que Le Roy fr quentait quelques-uns des penseurs les plus connus de l' poque (Condillac, Buffon, Diderot, Helv tius, d'Holbach), ainsi que des personnalit s de la haute soci t (en particulier Mme de Marchais), deux mondes don't l'influence est perceptible dans les Lettres sur les animaux. Celles-ci font cho non seulement aux crivains que leur auteur connaissit personnellement, mais aussi aux nombreux autres qu'il avait lus, notamment Montesquieu, Voltaire, Rousseau. Inspir et nourri de ces contacts scientifiques, litt raires et philosophiques, Le Roy a su s'en d gager pour d velopper sa propre pens e et, l'image de l'excellent accueil que les contemporains et la post rit ont r serv l'ouvrage, ses id es ne peuvent qu' veiller un vif int r t. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 269 severally through hearing, tasting, and smelling, so that we should have on our hands five spatially unrelated spaces. He can find no reason for abandoning the spontaneous commonsense conviction that the puffing I hear is that of the locomotive I am looking at, that the chocolate I am tasting is the one I have put in my mouth, that what I am smelling is the rose (...) I am seeing and also perhaps holding; and, to return to Berkeley, that I perceive the surface I am seeing to be the very one that I am touching with my finger. Mr. Armstrong seems to be laying down the basis of a general theory of perception, that no given perception can be reduced to the datum proper to the sense-organ used plus an associate, a guess, or an inference. To turn this negative statement into a positive one, to say what the activity is that grasps more than the presumed datum, and what makes it reliable, is, as the history of the theory of perception makes plain, desperately hard. Far from grumbling at Mr. Armstrong for not having gone forward to this task, I am grateful for his having given us a book that is so intelligent, acute, clear, stimulating, and blessedly concise--one that deserves to be read by anyone interested in Berkeley, or the theory of vision, or the theory of perception generally. T. E. Jzssov Hull, England Studies in the Philosophy of David Hume. A new edition. By Charles W. Hendel. (Indianapolis, New York: The Bobbs-Merrill Co., 1963. 14 x 21. Pp. li + 516.) Cette nouvelle 6dition des Studies a subi d'importants changements non seulement dans sa pr6sentation, mais aussi dans son esprit. Elle nous prouve combien la pens6e d'un homme se d6veloppe sans cesse et s'enrichit. L'interpr&ation d'un philosophe et la pens& m~me du philosophe ont connu et connaissent encore ces transformations. La pens& humaine ne consid~re jamais sa t$che comme achev&. C'est pourquoi nous ne devons jamais cesser d'ftendre le champ de nos &udes philosophiques pour provoquer la naissance de nouvelles comparaisons f&ondes. Nous y passons certes beaucoup de temps, en retour, nous discernons mieux les complexit6s de la nature humaine. Nous savions d6jh qu'il y avait plusieurs Platon, car le progr& de l'homme se poursuivait de dialogue en dialogue; nous savons maintenant qu'il y a plusieurs David Hume, et que le Hume de Kant ou le Hume du dernier siecle, ne peuvent plus 6tre les n6tres. Comme le remarque Charles Hendel, dans son introduction, vingt-cinq annfes ont suffi h renouveler l'interpr&ation que nous donnions de Hume. Aujourd'hui c'est l'imagination qui se forme l'habitude de repr&enter par un seul mot une collection d'id&s semblables et qui nous sugg~re d'user de l'id& de causalit~ pour interpr&er le retour de cons&utions analogues. C'est aussi l'imagination, plus que la raison, qui nous r&~le la probabilit~ d'un &6nement donn6. Hendel nous rapelle aussi que Buder pourrait bien avoir inspir6 ~t Hume l'importance morale de la sympathie, et que l'Alciphron de Berkeley aurait sugg6r6 le Cl~anthe des Dialogues sur la Religion Naturelle. Hendel a 6galement raison d'insister sur l'importance des interpr&ations de Norman Kemp Smith. Cette nouvelle et si 6rudite &ude de Hendel nous fait mieux comprendre ~ la fois les variations des pens6es de Hume, de Kemp Smith et de Hendel lui-m~me. Nous sommes ainsi mieux avertis des difficult6s de l'histoire de la philosophie, dues non seulement au d6veloppement des sciences, mais aussi du progr&s moral et spirituel, sujet h tant de fluctuations dans l'histoire et m~me, ~t une m~me epoque, d'homme h homme. Aussi cette nouvelle ~dition ne manquera pas d'apporter de nouvelles dart& h nombre de ses lecteurs. ANDV.a~ Lotas LEROY Sorbonne... (shrink)

This volume brings together a number of essays on various historical and thematic problems in the philosophy of Leibniz. The contributors include Prof. Leclerc, Milic Capek, Nicholas Rescher, N. L. Wilson, and Leroy E. Loemker. The book represents a kind of retrospective show of Prof. Loemker’s contribution to Leibniz scholarship, the other essays emphasizing points upon which he has commented less fully. As such the book serves three major functions: 1) it is a splendid introduction to Leibniz’ thought and (...) his historical context as a whole; 2) it complements nicely Professor Loemker’s recent study of the background to Leibniz’ thought ; 3) it puts into proper perspective another recent collection of English and American essays on Leibniz, in which Prof. Loemker is not represented. The essays are grouped under three headings, "Investigations," "Assessments," and "Historical Studies," corresponding in general to expository, critical and historical matters. (shrink)

Book reviewed in this article: Ethical Issues in Social Research. Edited by Tom L. Beauchamp, Ruth R. Faden, R. Jay Wallace, Jr., and LeRoy Walters. Baltimore: The Johns Hopkins University Press, 1982. xii + 436 pp. $25.00 (hardcover); $8.95 (paper). Ethics of Human Subject Research. Edited by Allan J. Kimmel, Jr. San Francisco: Jossey‐Bass, 1981. 106 pp. $6.95 (paper). Social Research Ethics. Edited by Martin Bulmer. New York: Holmes & Meier, 1982. xiv + 284 pp. $39.50 (hardcover); $14.50 (paper). (...) The Ethics of Social Research: Field‐work, Regulation and Publication. Edited by Joan E. Sieber. New York: Springer‐Verlag, 1982. x + 187 pp. $23.50 (hardcover). The Ethics of Social Research: Surveys and Experiments. Edited by Joan E. Sieber. New York: Springer‐Verlag, 1982. xii + 249 pp. $23.50 (hardcover). (shrink)

Part of the Philosophes series, this very useful introduction to Locke opens with a little ceremony which really does seem necessary in order to assure French readers of the relevance of foreign thinkers. It takes the form here of Voltaire's praise of Locke in his thirteenth Lettre philosophique. Voltaire's consecration however does serve to cast some eighteenth century light on Locke, which is an excellent way to begin the subject. There follows an outline of Locke's life and philosophy, with brief (...) considerations of the Letter on Tolerance and Two Treatises on Government, and an extended treatment of the four books of the Essay Concerning Human Understanding. Leroy uses a method of paraphrase with very limited commentary, a good device for getting inside a subject but one which involves a sacrifice in perspective. Some sixty pages of excerpts from the Essay are well chosen, indexed, and provided with topic headings. A minimal bibliography follows.--C. M. R. (shrink)

Розкрито сутність поняття «рейтинг». Доведено значущість рейтингової оцінки для суб’єктів фінансового ринку, зокрема для страхових компаній, потенційних страхувальників, інвесторів та кредиторів.

Aboriginal peoples are forever explaining themselves to non-Aboriginal people: telling their stories, explaining their beliefs and ceremonies, and introducing ideas that have never crossed the non-Aboriginal mind. Western knowledge operates from a linear, singular view; it views the world from order beneath chaos; it is very noun oriented; knowledge is about oneself in relation to everything else in a relativistic sense. Aboriginal knowledge has a very different “coming to know.” It is holistic and cyclical; it views the world from chaos (...) underneath order; its languages are process and action oriented. Knowledge is about participation in and with the natural world. (shrink)

SummaryCross-sectional studies in Australia and the Philippines and a longitudinal prospective study in a selected Australian sample of breast-feeding mothers have shown that basal serum prolactin concentrations are elevated during 15–21 months of lactational amenorrhoea.A predictive model of serum PRL levels and return of cyclic ovarian activity during full breast-feeding, partial breast-feeding and weaning has been developed from the results of breast-feeding behaviour and serum PRL, gonadotrophin and oestradiol measurements in 34 mothers breast-feeding on demand for a mean of 67 (...) weeks.Breast-feeding patterns influence serum PRL levels. Important factors during full breast-feeding are the age of the baby, the longest interval between feeds at night and total 24-hr suckling time, and following the introduction of supplements, the mean interval between feeds, together with the total 24-hr suckling time and the number of solid supplements per day.The precise mechanisms whereby breast-feeding regulates cyclic ovarian activity remain unknown. Gonadotrophin secretion appears to be quantitatively normal, but qualitative changes, secondary to altered hypothalamic activity, may be the most important factor. A direct inhibitory effect of PRL on ovarian follicular development and steroidogenesis remains possible.Ovulation with a normal luteal phase is probable for 30% of breast-feeding mothers before the first menses, but is unlikely before 6 months, provided breast-feeding is frequent day and night.Measurement of serum PRL is a sensitive index of the return of menstruation and fertility during lactation in the population studied. (shrink)

An empirical exploration of the effects on legislative structure, distribution of influence, power, and decision outcomes, of recent changes in the Congress and state legislatures. The book focuses on changes in rules, parties, and committees and the impact or lack of impact of these changes on subsequent activity. Originally published in 1978 by D.C. Heath and Company. Co-published with the Policy Studies Organization.

If Christian theology is that enterprise whose essential purpose is to understand the faith of the Christian Church, then it must approach that faith from the perspective not only of its transcendent source, but also as a human achievement, a creative interpretation of those events in which transcendent reality discloses itself for appropriation. Few theologians would deny that theology has to do primarily with the ways in which ultimate reality becomes manifest in human beings' faithful responses, in belief and trust, (...) to its self-disclosures, preparatory and decisive. But the implications of such a view are not always confronted straightforwardly, especially for the suitable normative principles by which theology must assess the adequacy of the church's expressions of its faith. This essay seeks to probe how an account of the Christian faith could proceed whose norm derives not from the revelatory source of faith but from the dynamic of human creativity within which alone faith's source, in being interpreted, becomes clear, cogent, and decisive for conscious existence. (shrink)